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Preventive effect of germinated barley foodstuff on diarrhea induced by
water-soluble dietary fiber in rats.
Biosci Biotechnol Biochem. 1997 Mar;61(3):449-54.
Kanauchi O, Nakamura T, Agata K, Fushiki T.
Applied Bioresearch Center, Kirin Brewery Co., Ltd., Gunma, Japan.
We investigated the preventive effect of germinated barley foodstuff (GBF) added
to the diet on diarrhea induced by the dietary water-soluble dietary fibers,
polydextrose, hemicellulose, and poly-acrylic acid sodium salt, in Sprague-Dawley
rats. The minimum content of GBF necessary for blocking diarrhea was 3% (by
weight) of the diet. Since GBF is mainly derived from the aleurone and scutellum
of malted barley, we assessed the physiological effects of the aleurone and
scutellum fractions derived from barley grains before and after germination. The
addition of fractions containing only germinated barley, and not barley
collected before germination, increased the fecal output and jejunal mucosal
protein content. The effects of malted barley were very similar to those of GBF.
It was concluded that germination was necessary to bring about the physiological
effects of GBF. Since non-lignified hemicellulose and Gln-rich protein were
newly synthesized during germination, these might have contributed to the
increased fecal output and jejunal mucosal protein content.
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