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Clinical
experiences in Sakai City Hospital during the massive outbreak of
enterohemorrhagic Escherichia coli O157 infections in Sakai City, 1996.
Pediatr Int 1999 Apr;41(2):213-7
Fukushima H, Hashizume T, Morita Y, Tanaka J, Azuma K, Mizumoto Y, Kaneno M,
Matsuura M, Konma K, Kitani T.
Department of Pediatrics, Sakai City Hospital, Osaka, Japan.
In the middle of July, 1996, a massive outbreak of hemorrhagic colitis (HC)
occurred among elementary schoolchildren in Sakai city. This is the most
widespread outbreak of O157 infection ever experienced to our knowledge. Lunch
foods supplied in the elementary schools in Sakai were contaminated by
Escherichia coli (E. coli) O157. One hundred and twenty-one cases developed
hemolytic uremic syndrome (HUS) from 12,680 symptomatic patients, including
putative secondary infections, and three girls died during this outbreak. Sakai
City Hospital is one of the core medical facilities in this community; hence,
425 children with HC were treated at the hospital. Antibiotics were used
extensively on all patients. Among them, 12 children developed HUS. All 425
children, including the patients with HUS, recovered without significant
sequelae. In the present paper, the clinical experiences during this massive
outbreak of E. coli O157 infection in Sakai City Hospital are described.
Note: A related article can be found
at:
"High
Court Orders Gov't to Redress Radish Sprout Growers", May 21/03, Kyodo
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