Sprouts and Cancer & Chemoprevention - General

Sprouts may play a role in cancer and chemoprevention treatment. For details about this important topic, see our catalog of additional research.

"4-Methylsulfanyl-3-butenyl isothiocyanate derived from glucoraphasatin is a potent inducer of rat hepatic phase II enzymes and a potential chemopreventive agent." Arch Toxicol. 2012 Feb;86(2):183-94. Epub 2011 Sep 30. Abdull Razis AF, De Nicola GR, Pagnotta E, Iori R, Ioannides C., Molecular Toxicology Group, Faculty of Health and Medical Sciences, University of Surrey, Guildford, Surrey, GU2 7XH, UK.

"Alkylperoxyl radical-scavenging activity of various flavonoids and other phenolic compounds: implications for the anti-tumor-promoter effect of vegetables.", J Agric Food Chem 1999 Feb;47(2):397-402, Sawa T, Nakao M, Akaike T, Ono K, Maeda H.Department of Microbiology, Kumamoto University School of Medicine, Japan.

"Anti-cancer Potential of Asian Brassicas" RIRDC Project No DAQ-307A, June 2004 - June 2007 Dr Tim O'Hare Queensland Department of Primary Industries and Fisheries, Queensland Horticulture Institute, Gatton Research Station.

"Anti-cancer Potential of Asian Brassicas, Glucosinolates & Chemoprevention"   A report for the Rural Industries Research and Development Corporation, by Tim O'Hare, Lesleigh Force, Lung Wong and Donald Irving, December 2006.

"Apigenin and cancer chemoprevention: Progress, potential and promise (Review)." Int J Oncol. 2007 Jan;30(1):233-45.Patel D, Shukla S, Gupta S.

"Broccoli" The World's Healthiest Foods, The George Mateljan Foundation, August 21, 2010.

"Broccoli sprouts in cancer prevention.", Nutr Rev 1998 Apr;56(4 Pt 1):127-30, Nestle M.

"Cancer Preventive Properties of Varieties of Brassica Oleracea: a Review", AM J Clin Nutrition 1994;59 pp. 1166-1170. Beecher, Christopher.

"Chinese cabbage extracts and sulforaphane can protect H2O2-induced inhibition of gap junctional intercellular communication through the inactivation of ERK1/2 and p38 MAP kinases." J Agric Food Chem. 2005 Oct 19;53(21):8205-10. Hwang JW, Park JS, Jo EH, Kim SJ, Yoon BS, Kim SH, Lee YS, Kang KS.

"Daikon, a promising anti-cancer vegetable" RIRDC Project No DAQ-342A, June 2007,  Dr Tim O'Hare Queensland Department of Primary Industries and Fisheries, Queensland Horticulture Institute, Gatton Research Station.

Dietary histone deacetylase inhibitors: From cells to mice to man. Semin Cancer Biol. 2007 May 5; Dashwood RH, Ho E. Linus Pauling Institute, Department of Environmental & Molecular Toxicology, Oregon State University, Corvallis, OR 97331, USA.

"Dietary phytoestrogens." Annu Rev Nutr 1997;17:353-81, Kurzer MS, Xu X., Department of Food Science and Nutrition, University of Minnesota, St. Paul 55108, USA.

"Effects of mustard sprouts and allylisothiocyanate on benzo(a)pyrene-induced DNA damage in human-derived cells: A model study with the single cell gel electrophoresis/Hep G2 assay.", Teratog Carcinog Mutagen 2003;23 Suppl 1:273-82, Uhl M, Laky B, Lhoste E, Kassie F, Kundi M, Knasmuller S., Insitute of Cancer Research, University of Vienna, Austria.

"Epidemiological studies on brassica vegetables and cancer risk." Cancer Epidemiol Biomarkers Prev. 1996 Sep;5(9):733-48. Verhoeven DT, Goldbohm RA, van Poppel G, Verhagen H, van den Brandt PA. Netherlands Organization for Applied Scientific Research, Nutrition and Food Research Institute, Zeist, The Netherlands.

"Evaporative light-scattering analysis of sulforaphane in broccoli samples: Quality of broccoli products regarding sulforaphane contents." J Agric Food Chem. 2006 Apr 5;54(7):2479-83. Nakagawa K, Umeda T, Higuchi O, Tsuzuki T, Suzuki T, Miyazawa T. Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.

"Glucosinolate Compostition and Anti-Cancer Potential of Daikon and Radish Sprouts" ISHS Acta Horticulturae 765: XXVII International Horticultural Congress - IHC2006: International Symposium on Plants as Food and Medicine: The Utilization and Development of Horticultural Plants for Human Health. T.J. O'Hare, L.S. Wong, L.E. Force, C.B. Gurung, D.E. Irving, D.J. Williams.

"Glucosinolate profiling of seed and sprouts of B. oleracea varieties used for food" Scientia Horticulturae, v.114(4):234-242, 2007. Bellostas, N.; Kachlicki, P.; Sorensen, J.C.; Sorensen, H.

"Glucosinolates in Brassica vegetables: The influence of the food supply chain on intake, bioavailability and human health".  Mol Nutr Food Res. 2008 Nov 26, Verkerk R, Schreiner M, Krumbein A, Ciska E, Holst B, Rowland I, De Schrijver R, Hansen M, Gerhäuser C, Mithen R, Dekker M.

"Health effects of phytoestrogens" Forum Nutr. 2005;(57):100-11. Branca F, Lorenzetti S. National Institute for Research on Food and Nutrition, Rome, Italy.

"Modulation of hepatic cytochromes P450 and phase II enzymes by dietary doses of sulforaphane in rats: Implications for its chemopreventive activity." Int J Cancer. 2005 Nov 10;117(3):356-62. Yoxall V, Kentish P, Coldham N, Kuhnert N, Sauer MJ, Ioannides C.

"Multi-targeted prevention of cancer by sulforaphane." Cancer Lett. 2008 Oct 8;269(2):291-304. Epub 2008 May 27. Clarke JD, Dashwood RH, Ho E. Department of Nutrition and Exercise Sciences, 117 Milam Hall, Oregon State University, Corvallis, OR 97331, USA.

"Natural Abundance Of L-Canavanine, An Active Anticancer Agent, in Alfalfa, Medicago Sativa", (L.)Pharmaceutical Biology, 2000, Vol.38, No.1, pp. 001-006, Gerald A. Rosenthal and Palesa Nkomo, University of Kentucky, Laboratory of Biochemical Ecology, Lexington, USA.

"Nutrition and cancer: a review of the evidence for an anti-cancer diet" Nutr J. 2004 Oct 20;3:19, Donaldson MS. Hallelujah Acres Foundation, 13553 Vantage Hwy, Ellensburg, WA 98926, USA.

"Phytoestrogen content of foods--a compendium of literature values.", Nutr Cancer 1996;26(2):123-48.Reinli K, Block G., Public Health Nutrition Program, University of California at Berkeley 94720, USA.

"Preparation of Selenium-enriched Sprouts and Identification of Their Selenium Species by High-performance Liquid Chromatography-Inductively Coupled Plasma Mass Spectrometry." Biosci Biotechnol Biochem. 2004 Jan;68(1):193-9.Sugihara S, Kondo M, Chihara Y, Yuji M, Hattori H, Yoshida M.Laboratory of Food and Nutritional Sciences, Department of Biotechnology, Faculty of Engineering, Kansai University.

"Potent activation of mitochondria-mediated apoptosis and arrest in S and M phases of cancer cells by a broccoli sprout extract." Tang L, Zhang Y, Jobson HE, Li J, Stephenson KK, Wade KL, Fahey JW. Department of Chemoprevention, Roswell Park Cancer Institute, Elm and Carlton Streets, Science 711, Buffalo, NY 14263, USA.

"Short acidic peptides isolated from wheat sprout chromatin and involved in the control of cell proliferation Characterization by infrared spectroscopy and mass spectrometry." Peptides. 2005 Jun 12; Calzuola I, Giavarini F, Sassi P, Angelis LD, Gianfranceschi GL, Marsili V.Dipartimento di Biologia Cellulare e Molecolare

"Sulforaphane and its analogues inhibit CYP1A1 and CYP1A2 activity induced by benzo[a]pyrene." J Biochem Mol Toxicol. 2009 Jan;23(1):18-28. Skupinska K, Misiewicz-Krzeminska I, Stypulkowski R, Lubelska K, Kasprzycka-Guttman T. National Medicines Institute, Chelmska 30/34, Warsaw, Poland.

"Total Phenolics Level, Antioxidant Activities and Cytotoxicity of Young Sprouts of Some Traditional Korean Salad Plants". Plant Foods Hum Nutr. 2008 Nov 19. Chon SU, Heo BG, Park YS, Kim DK, Gorinstein S. EFARINET Co. Ltd., BI Center, Chosun University, Gwangju, 501-759, South Korea.

"Wheat sprout extract-induced apoptosis in human cancer cells by proteasomes modulation." Biochimie. 2009 Sep;91(9):1131-44. Epub 2009 Jun 13 Bonfili L, Amici M, Cecarini V, Cuccioloni M, Tacconi R, Angeletti M, Fioretti E, Keller JN, Eleuteri AM.

"Wheat sprout extract induces changes on 20S proteasomes functionality."Amici M, Bonfili L, Spina M, Cecarini V, Calzuola I, Marsili V, Angeletti M, Fioretti E, Tacconi R, Gianfranceschi GL, Eleuteri AM. University of Camerino, Department of Biology M.C.A., 62032 Camerino (MC), Italy.