Sprouts and Prostrate Cancer

For coverage about sprouts and prostrate cancer, check out the scope of materials in our catalog of research on the topic.

"Broccoli" The World's Healthiest Foods, The George Mateljan Foundation, August 21, 2010.

"Broccoli consumption interacts with GSTM1 to perturb oncogenic signalling pathways in the prostate." PLoS One. 2008 Jul 2;3(7):e2568. Traka M, Gasper AV, Melchini A, Bacon JR, Needs PW, Frost V, Chantry A, Jones AM, Ortori CA, Barrett DA, Ball RY, Mills RD, Mithen RF. Phytochemicals and Health Programme, Institute of Food Research, Norwich Research Park, Norwich, United Kingdom.

Dietary histone deacetylase inhibitors: From cells to mice to man. Semin Cancer Biol. 2007 May 5; Dashwood RH, Ho E. Linus Pauling Institute, Department of Environmental & Molecular Toxicology, Oregon State University, Corvallis, OR 97331, USA.

"Dietary sulforaphane, a histone deacetylase inhibitor for cancer prevention." J Nutr. 2009 Dec;139(12):2393-6. Epub 2009 Oct 7. Ho E, Clarke JD, Dashwood RH. Department of Nutrition and Exercise Sciences, Oregon State University, Corvallis OR 97331, USA.

"Epidemiological studies on brassica vegetables and cancer risk." Cancer Epidemiol Biomarkers Prev. 1996 Sep;5(9):733-48. Verhoeven DT, Goldbohm RA, van Poppel G, Verhagen H, van den Brandt PA. Netherlands Organization for Applied Scientific Research, Nutrition and Food Research Institute, Zeist, The Netherlands.

"ERK and JNK signaling pathways are involved in the regulation of activator protein 1 and cell death elicited by three isothiocyanates in human prostate cancer PC-3 cells." Carcinogenesis. 2005 Nov 4, Xu C, Shen G, Yuan X, Kim JH, Gopalkrishnan A, Keum YS, Nair S, Kong AN.

"Feeding Tomato and Broccoli Powders Enriched with Bioactives Improves Bioactivity Markers in Rats" J Agric Food Chem. 2009 Aug 3. Liu AG, Volker SE, Jeffery EH, Erdman JW.

"Health effects of phytoestrogens" Forum Nutr. 2005;(57):100-11. Branca F, Lorenzetti S. National Institute for Research on Food and Nutrition, Rome, Italy.

"Hydrogen sulfide mediates the anti-survival effect of sulforaphane on human prostate cancer cells"  Toxicol Appl Pharmacol. 2011 Oct 8. Pei Y, Wu B, Cao Q, Wu L, Yang G.Department of Biology, Lakehead University, Thunder Bay, Canada; College of Life Science, Shanxi University, Taiyuan, China.

"Indole-3-carbinol induces a G1 cell cycle arrest and inhibits prostate-specific antigen production in human LNCaP prostate carcinoma cells", Cancer. 2003 Dec 1;98(11):2511-20.

Zhang J, Hsu B A JC, Kinseth B A MA, Bjeldanes LF, Firestone GL. Department of Molecular and Cell Biology, University of California at Berkeley, Berkeley, California 94720-3200, USA.

"Induction of cell cycle arrest in prostate cancer cells by the dietary compound isoliquiritigenin" J Med Food. 2009 Feb;12(1):8-14, Lee YM, Lim do Y, Choi HJ, Jung JI, Chung WY, Park JH.

"Isoliquiritigenin induces apoptosis by depolarizing mitochondrial membranes in prostate cancer cells." J Nutr Biochem. 2005 Dec 9; [Epub ahead of print], Jung JI, Lim SS, Choi HJ, Cho HJ, Shin HK, Kim EJ, Chung WY, Park KK, Park JH., Department of Food Science and Nutrition, Hallym University, Chuncheon 200-702, South Korea.

Isoliquiritigenin (ISL) inhibits ErbB3 signaling in prostate cancer cells. Biofactors. 2006;28(3-4):159-68. Jung JI, Chung E, Seon MR, Shin HK, Kim EJ, Lim SS, Chung WY, Park KK, Park JH. Department of Food Science and Nutrition and Silver Biotechnology Research Center, Hallym University, Chuncheon, Korea.

"Isoliquiritigenin inhibits migration and invasion of prostate cancer cells: possible mediation by decreased JNK/AP-1 signaling." J Nutr Biochem. 2008 Sep 26. Kwon GT, Cho HJ, Chung WY, Park KK, Moon A, Park JH. Department of Food Science and Nutrition, Hallym University, Chuncheon, 200-702, South Korea.

"Modulation of histone deacetylase activity by dietary isothiocyanates and allyl sulfides: Studies with sulforaphane and garlic organosulfur compounds." Environ Mol Mutagen. 2009 Feb 5. Nian H, Delage B, Ho E, Dashwood RH. Linus Pauling Institute, Oregon State University, Corvallis, Oregon.

"Molecular Targets and Anticancer Potential of Indole-3-Carbinol and Its Derivatives" Cell Cycle. 2005 Sep 6;4(9), Aggarwal BB, Ichikawa H.

"Multi-targeted prevention of cancer by sulforaphane." Cancer Lett. 2008 Oct 8;269(2):291-304. Epub 2008 May 27. Clarke JD, Dashwood RH, Ho E. Department of Nutrition and Exercise Sciences, 117 Milam Hall, Oregon State University, Corvallis, OR 97331, USA.

"Pharmacokinetics and pharmacodynamics of broccoli sprouts on the suppression of prostate cancer in transgenic adenocarcinoma of mouse prostate (TRAMP) mice: implication of induction of Nrf2, HO-1 and apoptosis and the suppression of Akt-dependent kinase pathway." Pharm Res. 2009 Oct;26(10):2324-31. Keum YS, Khor TO, Lin W, Shen G, Kwon KH, Barve A, Li W, Kong AN.

"Potent induction of phase 2 enzymes in human prostate cells by sulforaphane.", Cancer Epidemiol Biomarkers Prev 2001 Sep;10(9):949-54, Brooks JD, Paton VG, Vidanes G., Department of Urology, Stanford University Medical Center, Stanford, California 94305-5118, USA.

"Selenium enrichment of broccoli sprout extract increases chemosensitivity and apoptosis of LNCaP prostate cancer cells." BMC Cancer. 2009 Nov 30;9:414. Abdulah R, Faried A, Kobayashi K, Yamazaki C, Suradji EW, Ito K, Suzuki K, Murakami M, Kuwano H, Koyama H. Department of Public Health, Gunma University Graduate School of Medicine, Japan.

"Sulforaphane destabilizes the androgen receptor in prostate cancer cells by inactivating histone deacetylase 6." Proc Natl Acad Sci U S A. 2009 Sep 29;106(39):16663-8. Epub 2009 Sep 15. Gibbs A, Schwartzman J, Deng V, Alumkal J. Division of Hematology and Oncology, Oregon Health and Science University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.

"Sulforaphane inhibits histone deacetylase activity in BPH-1, LnCaP, and PC-3 prostate epithelial cells" Carcinogenesis. 2005 Nov 9. Myzak MC, Hardin K, Wang R, Dashwood RH, Ho E. Linus Pauling Institute, Oregon State University, Corvallis, OR 97331; Molecular and Cellular Biology Program, Oregon State University, Corvallis, OR 97331.

"Sulforaphane inhibits prostate carcinogenesis and pulmonary metastasis in TRAMP mice in association with increased cytotoxicity of natural killer cells."Cancer Res. 2009 Mar 1;69(5):2117-25. Epub 2009 Feb 17. Singh SV, Warin R, Xiao D, Powolny AA, Stan SD, Arlotti JA, Zeng Y, Hahm ER, Marynowski SW, Bommareddy A, Desai D, Amin S, Parise RA, Beumer JH, Chambers WH. Department of Pharmacology and Chemical Biology, University of Pittsburgh School of Medicine, USA.

"Temporal changes in gene expression induced by sulforaphane in human prostate cancer cells" Prostate. 2008 Oct 30. Bhamre S, Sahoo D, Tibshirani R, Dill DL, Brooks JD. Department of Urology, Stanford University, Stanford, California.

"Wheat sprout extract induces changes on 20S proteasomes functionality."Amici M, Bonfili L, Spina M, Cecarini V, Calzuola I, Marsili V, Angeletti M, Fioretti E, Tacconi R, Gianfranceschi GL, Eleuteri AM. University of Camerino, Department of Biology M.C.A., 62032 Camerino (MC), Italy.