Sprouts and Skin Cancer

For insights about sprouts and skin cancer, we invite you to take a look at our centralized list of research articles on the topic.

"Broccoli" The World's Healthiest Foods, The George Mateljan Foundation, August 21, 2010.

"Impact of Nrf2 on UVB-induced skin inflammation/photoprotection and photoprotective effect of sulforaphane."; Mol Carcinog. 2011 Jun;50(6):479-86. doi: 10.1002/mc.20725. Epub 2010 Dec 28. Saw CL,Huang MT,Liu Y, Khor TO, Conney AH, Kong AN. Center for Cancer Prevention Research, Rutgers, The State University of New Jersey, Piscataway, New Jersey 08854, USA.

Induction of the phase 2 response in mouse and human skin by sulforaphane-containing broccoli sprout extracts. Cancer Epidemiol Biomarkers Prev. 2007 Apr;16(4):847-51. Dinkova-Kostova AT, et.al. Department of Pharmacology and Molecular Sciences, School of Medicine, Johns Hopkins University, 725 North Wolfe Street, Baltimore, MD 21205, USA.

"Inhibition of activator protein-1 by sulforaphane involves interaction with cysteine in the cFos DNA-binding domain: implications for chemoprevention of UVB-induced skin cancer."Cancer Res. 2009 Sep 1;69(17):7103-10. Epub 2009 Aug 11. Dickinson SE, Melton TF, Olson ER, Zhang J, Saboda K, Bowden GT. Arizona Cancer Center, University of Arizona, Tucson, Arizona 85724, USA.

"Protection against UV-light-induced skin carcinogenesis in SKH-1 high-risk mice by sulforaphane-containing broccoli sprout extracts." Cancer Lett. 2005 Nov 2; Dinkova-Kostova AT, Jenkins SN, Fahey JW, Ye L, Wehage SL, Liby KT, Stephenson KK, Wade KL, Talalay P.

"Sulforaphane and 2-oxohexyl isothiocyanate induce cell growth arrest and apoptosis in L-1210 leukemia and ME-18 melanoma cells", Oncol Rep. 2003 Nov-Dec;10(6):2045-50. Misiewicz I, Skupinska K, Kasprzycka-Guttman T. Confocal Microscopy Laboratory, National Institute of Public Health, 00-725 Warsaw, Chelmska 30/34, Poland.

"Sulforaphane mobilizes cellular defenses that protect skin against damage by UV radiation" Proc Natl Acad Sci U S A. 2007 Oct 30;104(44):17500-17505.Talalay P, Fahey JW, Healy ZR, Wehage SL, Benedict AL, Min C, Dinkova-Kostova AT.

"Sulforaphane suppresses ultraviolet B-induced inflammation in HaCaT keratinocytes and HR-1 hairless mice." J Nutr Biochem. 2009 Jul 1. Shibata A, Nakagawa K, Yamanoi H, Tsuduki T, Sookwong P, Higuchi O, Kimura F, Miyazawa T. Food and Biodynamic Chemistry Laboratory, Graduate School of Agricultural Science, Tohoku University, Sendai 981-8555, Japan.

"Sulforaphane but not ascorbigen, indole-3-carbinole and ascorbic acid activates the transcription factor Nrf2 and induces phase-2 and antioxidant enzymes in human keratinocytes in culture." Exp Dermatol. 2009 Jun 23. Wagner AE, Ernst I, Iori R, Desel C, Rimbach G. Institute of Human Nutrition and Food Science, Christian-Albrechts-University, Kiel, Germany. Experimental Dermatology 2009.